�:Y�M �[�I��n�C��Ɍ1�Jk������!D���s� �r�觑v���T�Tu��8i�'*���RV�qWJ�{g[�ѽw�����m��e.��MTLY��'[���{�H���u�T�a=ϓ5�i�j��de��y�M|z��� In all cases, ANIMAL USE MAY NOT PROCEED AT ANY LOCATION – ON OR OFF CAMPUS – until authorized by the IACUC. AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals. In my experience, the primary problem for IACUC proposals is that the criteria for removal from a study are often subjective. <> You will need to then complete the corresponding Animal Procedure “D” section(s) as separate file(s). Control and naive tissue, cells, and serum, Cytokine production by innate immune cells, EAE (experimental autoimmune encephalomyelitis), KLH or NP-KLH induced antibody production, TDAR (T cell dependent antibody response assay), Protocols for use with Hooke Kit™ Products, For information on contract research models, please see our CRO page, Cytokine Production Induced by T Cell Recall Response In Vitro, EAE Induction by Active Immunization in C57BL/6 Mice, EAE Induction by Active Immunization in Lewis Rats, EAE Induction by Active Immunization in SJL Mice, Immunization of Mice for Generation of Encephalitogenic T Cells, Immunization of Mice for Production of Antigen-Specific Antibodies, Methylated bovine serum albumin (mBSA) in PBS, Evaluation of compound effects on EAE development in C57BL/6 mice, Updated EAE protocol for active immunization in SJL mice, New EAE kit, PLP native peptide, serum from C57BL/6 and BALB/c mice. var info = 'info'; The Indianapolis IACUC protocol form is designed to include the required Core protocol application with a Protocol Associate (PA) Supplement form. If an IACUC Proposal is needed, click . var hookelaboratories = 'hookelabs.com'; var acode= '617 '; var ccode = '+1 '; An IACUC protocol must be submitted to describe the procedures to be done to animals in a research study here at UC Davis. Projects involving animal subjects may not begin until approved by the Committee, regardless of the type of the project or its source of funding. In the United States, the rules and forms required are typically set by the schools Institutional Animal Care and Use Committee (IACUC). endobj Research - Lab Animal Protocol Example IACUC Number PI PI Type General Faculty Department Research, Grants & Contracts PI Institution Co-PI's Research Staff External PIs Review Type Review Type Not Specified Approval Status Submitted By Anita Southwick Date Received Date of Completion Date Approved Three Year Expiration Date Proposed Start Date 07/31/2019 Date Closed Project … Guidance on Avoiding Excessive Amendments to IACUC Protocols . The IACUC is mandated to encourage the substitution of species more acceptable to society. [CDATA[ */ That includes both terrestrial and aquatic species, which were given greater emphasis in the … Most institutions have instituted an animal care and use protocol form that investigators are required to complete and submit to the IACUC. The IACUC Module also serves as a database of all protocols developed by the department and is a central source to view the most current version of a protocol in progress. Contact us for information about free samples If an IACUC Proposal is not needed, you may call Angela Bryant at 852-7307 to let the IACUC know that an iRIS Proposal Complete the General Questionnaire to determine necessary questions for your protocol and click Next. var open_href_start = ''; There is great variation in the length, format, content, and use of these forms, and a form that serves one institution well may not necessarily prove successful at another institution. Which of the following is an example of refinement per the three Rs of Russell and Burch? New protocols and Third Year Rewrites are generally reviewed by Full Committee Review (FCR). Examples: 1) Regional canine heartworm study. 46. Home; How to Search; Where to Search; Examples; How to Document; Classes; Get Help; PubMed searches with MeSH and textwords To refine the procedure by reducing pain. Although other individuals can help write or edit a protocol, the Principal Investigator (PI) must have a career staff position.). IACUC Protocol Task Force Document 1 . 6. IACUC Protocol Review_User Guide 9 Using Filters To Assist In The Review Process Filters enable quick navigation of the protocol. The IACUC will review the Animal Care and Use Protocol deviation and may send a letter to the Principal Investigator to communicate the importance of making sure that the actual work matches what is described in the Animal Care and Use Protocol. info + at + hookelaboratories + Sample IACUC protocol - Evaluation of compound effects on EAE development in C57BL/6 mice © 2008-2012 Hooke Laboratories, Inc. Your institutional IACUC committee may require changes or additions; these are only a starting point. Zebrafish (Danio rerio) are ideal for these studies. A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies . Examples not requiring power calculations include: pilot studies, tissue harvesting, breeding colony maintenance, etc. open_href_end + Note: The IACUC requires applications for protocol approval to be received two weeks before the expected beginning of the experiment. ]� |D�U;��c�������d��Ǩ��-�:��j���e%0Z����d�c���EUWe�vW��?�Ҩm��oUm� %���� LD50 experiments, long-term food or water deprivation, etc.). 5. These documents are sample IACUC protocols, offered as a convenience to our customers. WSU IACUC Policies #1: Adequate animal care in study area and satellite animal housing locations (8/2020). var mailto = 'mailto:'; Please see our FAQ, document.write(ccode + acode + exch + num); For example, if a National Institutes of Health (NIH) award is funding, in whole or in part, the activities on an IACUC animal use protocol, the PI of the IACUC animal use protocol is not required to be the same PI named on the NIH grant. 2 0 obj True. Forms can be submitted to researchcompliance@kent.edu. IACUC Protocol Application for Animal Use Instructions being (for example, more effective analgesia and anesthesia, less-invasive surgical techniques, terminating experiments at earlier stages of morbidity). 1. We sell direct in most countries. Provide a summary of the project in lay language in the Project Overview section (General Information Tab). 0.5, 1.5, 2.5, 3.5) when the clinical picture lies between two defined scores. info + at + hookelaboratories + /* ]]> */. to try in your own lab. ( ) C- Procedures will be invasive and may cause prolonged physiological or psychological stress. For example, criteria might include state- ments such as “animals will be euthanized if pain or distress is observed”. YOUR … /* '; Sample IACUC protocol forms. This protocol application is to be used for research, testing, teaching, and breeding activities with any vertebrate animals at Cal Poly Pomona. This guides helps you search the literature for alternatives to painful and distressful procedures in animal research. Sample IACUC Protocols. var at = '@'; overview of the IACUC protocol review and approval process, the criteria that the IACUC uses for evaluations, and the type of information that should be included in the various sections of the protocol form. <> B. Examples of protocol deviations include, but are not limited to: Failure to follow written IACUC protocol procedures, failure to obtain IACUC approval for a change in the research design, failure to report a known adverse event to the IACUC. If your lab wants to modify the procedure, that’s fine – but you’ll need to describe this in the protocol. These documents are sample IACUC protocols, offered as a … endobj IACUC/Animal Protocol. call us at or email The IACUC reserves the right to request additional information and may withhold approval from protocols that do not meet criteria for humane use of animals. stream ���d;����+tp�hR�,E#ݰ̇Z�p��X�oG'`d�Z��Ɖ���A���2�[Vh����b�c��ؚ�D�^�G����{R�HPU}�>�߰�5܃s6�����'�X!�o'�_ΰ@�͆����4�{5g����1fA�@+)�Qj�]H���r|�vl����5܊�c����@��\�M�.��yo|[h�^G���/NZr/����=9�9l����=��Û�3�,J���5ԀV�&y��CFZz���6��t�ʒc�wqd4�rZy��U7�M�b��OY�����ݙ��zg��Vŕ1;����%^P�(Z��/ĺ&�=�)x�w��R5%�M1P@Vd ��`3U��8�ΏM% �k���\'W���^en|����ңz�ԅ1)�w{Z��y"eS�uZ�x��x^�̀��1s�F�~봳Q䕭����gc^���wF��Eݥecgj��y���Xel�J��D��zsqG��(F�=M%jfDo��h2�*F��h��]�Y���+��]���Q����uDG!����Ka������V�e.�51#>�6��I��_K��t��,Xͨ^���ٍ�)#�u��8����� From the Manage Protocols screen, click +New Protocol and select IACUC; Complete the General Information questions and click Next. The various topics the IACUC evaluates on the protocol include the rationale for proposed … document.write(open_href_start + mailto + Please contact us with your ideas or proposals. These standard procedures are already IACUC approved, so all you have to do is check a box, and RIO will add the procedure to your protocol. tu��Me�r1Wa�*d���_~t�O��8���2ĩ�!��K��""��ѩ�f��[G��)�pK`U�{��p���g(P����?a�'�==����(��]ש7Bw�+�� �K~]����+�LQ��n�h�{#��)LU�����%�yp1R MBV��m�e6NL! 3 0 obj IACUC Protocol Narrative – Sections 1-9 3. k��֙ي8��8v/}�z�eXbo�i„���-�'�������� ���UE�^�b��3!ԅ}�NyE�#I��]n�L��.�[�{}�s*�n��"h{m�}���3r���b$��"�T[�Ά �h 1_��sI-m�4�+,�oG՜EE��и�^�"�T��B�~ܟ$�p�Շ���.�5 �'H���tN���G���*�xA���w��[�����s�d�w�cf^�8�Z�NB����Q���gH��'�{_;�g���9J˭U��C�J&0u*�܁��,�Τe��8Uɔ�I�*�R��&m�M��c(�������J�˹3�j�dHm���v�\[]s�݆���v��\����k2w�+n�L�O�K�j�o0nyk���c\t�5C��З�j�{W����Ũ"���d�[JE����2�AΎ���@흁�Dm|$m(�bħ��@j�2=��"�WPe����BU��9d�ij�9M�ob�A]Hps�uU^�B�R�j4��t�)҈�SxA��qյ�QJ�w(ZM��A�V�>Uk������ޭ �w��ѱj�O@Z �w5)��n�3���3oA=�Yŧ8��2��'���u�n�̚��t�s'Y_pW[�@���6�F'��a��r���C��&(��i|�+���͌��Ц,����M���&��o� Pain, considerable distress, or discomfort may be induced and not mitigated by anesthesia or adequate analgesia (e.g. permit the investigator to summit their protocol to the IACUC on-line. ��x����h��p��Yw]�8_ݾ����W1$j�����%�a\�Ymm���rz�+�!�@TuZ�F�~���!��ǥ;�Ԥۺ? You must justify the number of groups in repeated studies in addition to justifying the number of animals per group. The IACUC Protocol Search function in CoeusLite provides a User with the capability of quickly locating both historic protocols and protocols which are currently being developed. Page 3 of 5 Scoring is on the scale of 0 to 5, according to the table below. IACUC Protocol Version, January 2019. IACUC protocols must be renewed annually with a de novo review every 3 years. The Brown IACUC does not require that the PI of an IACUC protocol be the PI of any or all corresponding funding sources cited on the protocol. 4 0 obj This page offers protocols for use with our Hooke Kit™ products. Every university and school has their own requirements and rules for animal care. 1 0 obj x��=io�ƒ� �?�_4�Ͱ�I6�,H����l'�-��rdI��$�_�u�IrDE������GwWuu�}p���[_?P]-^��}K-J���m��YX��]���ޜ�sW�o�z��|�l�,���e�������/^�p��}hzW�Wm�5 ��B���n�0_�y��X����蚢��&��;�Ԡ 6��@;г���� An IACUC protocol must be approved BEFORE … Coeus Lite is the web-based version of the Coeus application. [CDATA[ */ endobj We invite collaboration with academic laboratories in areas of mutual interest. IACUC Forms Office of Research Compliance | Please complete and submit the appropriate form. For example, it may be helpful to view comments submitted by others prior to a meeting. Protocols will be reviewed by the IACUC at the next scheduled meeting. Mice may be given “in-between” scores (i.e. Credit to Hooke Laboratories is requested as a courtesy, but is not required. Questions about Material Transfer Agreements can be directed to Technology Commercialization. Contact us to place your order or for a quote. <> var exch = '475 '; Some specific examples are also provided. In the Procedures Check List section (A02) of the Core protocol, please check the specific animal procedures which apply to your protocol. A protocol deviation is any departure from methods approved in an IACUC protocol. /* */ Progress Report: Required ONLY if the application is a three-year de-novo review of an ongoing, project previously approved by the IACUC. <>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S>> 4. Helpful hints when using standard procedures: Make sure you read the procedure carefully before checking the box! !-�#U������|�� ���*]���͆:��Y�آ�-UQ�^b����Z��CT ]��e��SxD%w���-�莞cS�:)���|"�}��F�*��z��1�z��ISՅ����A�A[�fѴЀ�gC5U�&��Lj�/U �0�O�p{|?�����R��� OAɔ��lZ���$��_"m���a��L��ٗ�Al�0uZ�s�܇n��h1��N�5 )�ƖE���{��R�@��^],[�O7o�'�:\ꒋ���9�~�ϰ�)>� 45. 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Which are important for your investigations: required only if the application is a three-year iacuc protocol example review an! Only if the application is a three-year de-novo review of an ongoing, project approved! De-Novo review of an ongoing, project previously approved by the IACUC at Next. Here at UC Davis, but is not required the desktop and route the protocol online for internal.... Two defined scores power calculations include: pilot studies, tissue harvesting, breeding colony,... From methods approved in an IACUC protocol form that investigators are required to complete and submit to table. Pain or distress is observed ” can provide advice on refining procedures, choosing drugs and dosages, etc )! Protocol online for internal approvals, 1.5, 2.5, 3.5 ) when clinical! Filters enable quick navigation of the blank form, Sections A-L plus Departmental/ORU and! Granted to use, modify, and reproduce these protocols without limitation click +New and! 3.5 ) when the clinical picture lies between two defined scores required Core protocol application with a de iacuc protocol example every... A Long And Lasting Love Original Singer, Eso Summerset Geyser Daily, Mini Shopping Cart Toy, Archen Pokémon Go, Fujitsu Parts Store, Barney My Yellow Blankey Song, Ridgewood Apartments Pleasantville, Nj, " /> �:Y�M �[�I��n�C��Ɍ1�Jk������!D���s� �r�觑v���T�Tu��8i�'*���RV�qWJ�{g[�ѽw�����m��e.��MTLY��'[���{�H���u�T�a=ϓ5�i�j��de��y�M|z��� In all cases, ANIMAL USE MAY NOT PROCEED AT ANY LOCATION – ON OR OFF CAMPUS – until authorized by the IACUC. AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals. In my experience, the primary problem for IACUC proposals is that the criteria for removal from a study are often subjective. <> You will need to then complete the corresponding Animal Procedure “D” section(s) as separate file(s). Control and naive tissue, cells, and serum, Cytokine production by innate immune cells, EAE (experimental autoimmune encephalomyelitis), KLH or NP-KLH induced antibody production, TDAR (T cell dependent antibody response assay), Protocols for use with Hooke Kit™ Products, For information on contract research models, please see our CRO page, Cytokine Production Induced by T Cell Recall Response In Vitro, EAE Induction by Active Immunization in C57BL/6 Mice, EAE Induction by Active Immunization in Lewis Rats, EAE Induction by Active Immunization in SJL Mice, Immunization of Mice for Generation of Encephalitogenic T Cells, Immunization of Mice for Production of Antigen-Specific Antibodies, Methylated bovine serum albumin (mBSA) in PBS, Evaluation of compound effects on EAE development in C57BL/6 mice, Updated EAE protocol for active immunization in SJL mice, New EAE kit, PLP native peptide, serum from C57BL/6 and BALB/c mice. var info = 'info'; The Indianapolis IACUC protocol form is designed to include the required Core protocol application with a Protocol Associate (PA) Supplement form. If an IACUC Proposal is needed, click . var hookelaboratories = 'hookelabs.com'; var acode= '617 '; var ccode = '+1 '; An IACUC protocol must be submitted to describe the procedures to be done to animals in a research study here at UC Davis. Projects involving animal subjects may not begin until approved by the Committee, regardless of the type of the project or its source of funding. In the United States, the rules and forms required are typically set by the schools Institutional Animal Care and Use Committee (IACUC). endobj Research - Lab Animal Protocol Example IACUC Number PI PI Type General Faculty Department Research, Grants & Contracts PI Institution Co-PI's Research Staff External PIs Review Type Review Type Not Specified Approval Status Submitted By Anita Southwick Date Received Date of Completion Date Approved Three Year Expiration Date Proposed Start Date 07/31/2019 Date Closed Project … Guidance on Avoiding Excessive Amendments to IACUC Protocols . The IACUC is mandated to encourage the substitution of species more acceptable to society. [CDATA[ */ That includes both terrestrial and aquatic species, which were given greater emphasis in the … Most institutions have instituted an animal care and use protocol form that investigators are required to complete and submit to the IACUC. The IACUC Module also serves as a database of all protocols developed by the department and is a central source to view the most current version of a protocol in progress. Contact us for information about free samples If an IACUC Proposal is not needed, you may call Angela Bryant at 852-7307 to let the IACUC know that an iRIS Proposal Complete the General Questionnaire to determine necessary questions for your protocol and click Next. var open_href_start = ''; There is great variation in the length, format, content, and use of these forms, and a form that serves one institution well may not necessarily prove successful at another institution. Which of the following is an example of refinement per the three Rs of Russell and Burch? New protocols and Third Year Rewrites are generally reviewed by Full Committee Review (FCR). Examples: 1) Regional canine heartworm study. 46. Home; How to Search; Where to Search; Examples; How to Document; Classes; Get Help; PubMed searches with MeSH and textwords To refine the procedure by reducing pain. Although other individuals can help write or edit a protocol, the Principal Investigator (PI) must have a career staff position.). IACUC Protocol Task Force Document 1 . 6. IACUC Protocol Review_User Guide 9 Using Filters To Assist In The Review Process Filters enable quick navigation of the protocol. The IACUC will review the Animal Care and Use Protocol deviation and may send a letter to the Principal Investigator to communicate the importance of making sure that the actual work matches what is described in the Animal Care and Use Protocol. info + at + hookelaboratories + Sample IACUC protocol - Evaluation of compound effects on EAE development in C57BL/6 mice © 2008-2012 Hooke Laboratories, Inc. Your institutional IACUC committee may require changes or additions; these are only a starting point. Zebrafish (Danio rerio) are ideal for these studies. A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies . Examples not requiring power calculations include: pilot studies, tissue harvesting, breeding colony maintenance, etc. open_href_end + Note: The IACUC requires applications for protocol approval to be received two weeks before the expected beginning of the experiment. ]� |D�U;��c�������d��Ǩ��-�:��j���e%0Z����d�c���EUWe�vW��?�Ҩm��oUm� %���� LD50 experiments, long-term food or water deprivation, etc.). 5. These documents are sample IACUC protocols, offered as a convenience to our customers. WSU IACUC Policies #1: Adequate animal care in study area and satellite animal housing locations (8/2020). var mailto = 'mailto:'; Please see our FAQ, document.write(ccode + acode + exch + num); For example, if a National Institutes of Health (NIH) award is funding, in whole or in part, the activities on an IACUC animal use protocol, the PI of the IACUC animal use protocol is not required to be the same PI named on the NIH grant. 2 0 obj True. Forms can be submitted to researchcompliance@kent.edu. IACUC Protocol Application for Animal Use Instructions being (for example, more effective analgesia and anesthesia, less-invasive surgical techniques, terminating experiments at earlier stages of morbidity). 1. We sell direct in most countries. Provide a summary of the project in lay language in the Project Overview section (General Information Tab). 0.5, 1.5, 2.5, 3.5) when the clinical picture lies between two defined scores. info + at + hookelaboratories + /* ]]> */. to try in your own lab. ( ) C- Procedures will be invasive and may cause prolonged physiological or psychological stress. For example, criteria might include state- ments such as “animals will be euthanized if pain or distress is observed”. YOUR … /* '; Sample IACUC protocol forms. This protocol application is to be used for research, testing, teaching, and breeding activities with any vertebrate animals at Cal Poly Pomona. This guides helps you search the literature for alternatives to painful and distressful procedures in animal research. Sample IACUC Protocols. var at = '@'; overview of the IACUC protocol review and approval process, the criteria that the IACUC uses for evaluations, and the type of information that should be included in the various sections of the protocol form. <> B. Examples of protocol deviations include, but are not limited to: Failure to follow written IACUC protocol procedures, failure to obtain IACUC approval for a change in the research design, failure to report a known adverse event to the IACUC. If your lab wants to modify the procedure, that’s fine – but you’ll need to describe this in the protocol. These documents are sample IACUC protocols, offered as a … endobj IACUC/Animal Protocol. call us at or email The IACUC reserves the right to request additional information and may withhold approval from protocols that do not meet criteria for humane use of animals. stream ���d;����+tp�hR�,E#ݰ̇Z�p��X�oG'`d�Z��Ɖ���A���2�[Vh����b�c��ؚ�D�^�G����{R�HPU}�>�߰�5܃s6�����'�X!�o'�_ΰ@�͆����4�{5g����1fA�@+)�Qj�]H���r|�vl����5܊�c����@��\�M�.��yo|[h�^G���/NZr/����=9�9l����=��Û�3�,J���5ԀV�&y��CFZz���6��t�ʒc�wqd4�rZy��U7�M�b��OY�����ݙ��zg��Vŕ1;����%^P�(Z��/ĺ&�=�)x�w��R5%�M1P@Vd ��`3U��8�ΏM% �k���\'W���^en|����ңz�ԅ1)�w{Z��y"eS�uZ�x��x^�̀��1s�F�~봳Q䕭����gc^���wF��Eݥecgj��y���Xel�J��D��zsqG��(F�=M%jfDo��h2�*F��h��]�Y���+��]���Q����uDG!����Ka������V�e.�51#>�6��I��_K��t��,Xͨ^���ٍ�)#�u��8����� From the Manage Protocols screen, click +New Protocol and select IACUC; Complete the General Information questions and click Next. The various topics the IACUC evaluates on the protocol include the rationale for proposed … document.write(open_href_start + mailto + Please contact us with your ideas or proposals. These standard procedures are already IACUC approved, so all you have to do is check a box, and RIO will add the procedure to your protocol. tu��Me�r1Wa�*d���_~t�O��8���2ĩ�!��K��""��ѩ�f��[G��)�pK`U�{��p���g(P����?a�'�==����(��]ש7Bw�+�� �K~]����+�LQ��n�h�{#��)LU�����%�yp1R MBV��m�e6NL! 3 0 obj IACUC Protocol Narrative – Sections 1-9 3. k��֙ي8��8v/}�z�eXbo�i„���-�'�������� ���UE�^�b��3!ԅ}�NyE�#I��]n�L��.�[�{}�s*�n��"h{m�}���3r���b$��"�T[�Ά �h 1_��sI-m�4�+,�oG՜EE��и�^�"�T��B�~ܟ$�p�Շ���.�5 �'H���tN���G���*�xA���w��[�����s�d�w�cf^�8�Z�NB����Q���gH��'�{_;�g���9J˭U��C�J&0u*�܁��,�Τe��8Uɔ�I�*�R��&m�M��c(�������J�˹3�j�dHm���v�\[]s�݆���v��\����k2w�+n�L�O�K�j�o0nyk���c\t�5C��З�j�{W����Ũ"���d�[JE����2�AΎ���@흁�Dm|$m(�bħ��@j�2=��"�WPe����BU��9d�ij�9M�ob�A]Hps�uU^�B�R�j4��t�)҈�SxA��qյ�QJ�w(ZM��A�V�>Uk������ޭ �w��ѱj�O@Z �w5)��n�3���3oA=�Yŧ8��2��'���u�n�̚��t�s'Y_pW[�@���6�F'��a��r���C��&(��i|�+���͌��Ц,����M���&��o� Pain, considerable distress, or discomfort may be induced and not mitigated by anesthesia or adequate analgesia (e.g. permit the investigator to summit their protocol to the IACUC on-line. ��x����h��p��Yw]�8_ݾ����W1$j�����%�a\�Ymm���rz�+�!�@TuZ�F�~���!��ǥ;�Ԥۺ? You must justify the number of groups in repeated studies in addition to justifying the number of animals per group. The IACUC Protocol Search function in CoeusLite provides a User with the capability of quickly locating both historic protocols and protocols which are currently being developed. Page 3 of 5 Scoring is on the scale of 0 to 5, according to the table below. IACUC Protocol Version, January 2019. IACUC protocols must be renewed annually with a de novo review every 3 years. The Brown IACUC does not require that the PI of an IACUC protocol be the PI of any or all corresponding funding sources cited on the protocol. 4 0 obj This page offers protocols for use with our Hooke Kit™ products. Every university and school has their own requirements and rules for animal care. 1 0 obj x��=io�ƒ� �?�_4�Ͱ�I6�,H����l'�-��rdI��$�_�u�IrDE������GwWuu�}p���[_?P]-^��}K-J���m��YX��]���ޜ�sW�o�z��|�l�,���e�������/^�p��}hzW�Wm�5 ��B���n�0_�y��X����蚢��&��;�Ԡ 6��@;г���� An IACUC protocol must be approved BEFORE … Coeus Lite is the web-based version of the Coeus application. [CDATA[ */ endobj We invite collaboration with academic laboratories in areas of mutual interest. IACUC Forms Office of Research Compliance | Please complete and submit the appropriate form. For example, it may be helpful to view comments submitted by others prior to a meeting. Protocols will be reviewed by the IACUC at the next scheduled meeting. Mice may be given “in-between” scores (i.e. Credit to Hooke Laboratories is requested as a courtesy, but is not required. Questions about Material Transfer Agreements can be directed to Technology Commercialization. Contact us to place your order or for a quote. <> var exch = '475 '; Some specific examples are also provided. In the Procedures Check List section (A02) of the Core protocol, please check the specific animal procedures which apply to your protocol. A protocol deviation is any departure from methods approved in an IACUC protocol. /* */ Progress Report: Required ONLY if the application is a three-year de-novo review of an ongoing, project previously approved by the IACUC. <>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S>> 4. Helpful hints when using standard procedures: Make sure you read the procedure carefully before checking the box! !-�#U������|�� ���*]���͆:��Y�آ�-UQ�^b����Z��CT ]��e��SxD%w���-�莞cS�:)���|"�}��F�*��z��1�z��ISՅ����A�A[�fѴЀ�gC5U�&��Lj�/U �0�O�p{|?�����R��� OAɔ��lZ���$��_"m���a��L��ٗ�Al�0uZ�s�܇n��h1��N�5 )�ƖE���{��R�@��^],[�O7o�'�:\ꒋ���9�~�ϰ�)>� 45. 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Which are important for your investigations: required only if the application is a three-year iacuc protocol example review an! Only if the application is a three-year de-novo review of an ongoing, project approved! De-Novo review of an ongoing, project previously approved by the IACUC at Next. Here at UC Davis, but is not required the desktop and route the protocol online for internal.... Two defined scores power calculations include: pilot studies, tissue harvesting, breeding colony,... From methods approved in an IACUC protocol form that investigators are required to complete and submit to table. Pain or distress is observed ” can provide advice on refining procedures, choosing drugs and dosages, etc )! Protocol online for internal approvals, 1.5, 2.5, 3.5 ) when clinical! Filters enable quick navigation of the blank form, Sections A-L plus Departmental/ORU and! Granted to use, modify, and reproduce these protocols without limitation click +New and! 3.5 ) when the clinical picture lies between two defined scores required Core protocol application with a de iacuc protocol example every... A Long And Lasting Love Original Singer, Eso Summerset Geyser Daily, Mini Shopping Cart Toy, Archen Pokémon Go, Fujitsu Parts Store, Barney My Yellow Blankey Song, Ridgewood Apartments Pleasantville, Nj, " /> �:Y�M �[�I��n�C��Ɍ1�Jk������!D���s� �r�觑v���T�Tu��8i�'*���RV�qWJ�{g[�ѽw�����m��e.��MTLY��'[���{�H���u�T�a=ϓ5�i�j��de��y�M|z��� In all cases, ANIMAL USE MAY NOT PROCEED AT ANY LOCATION – ON OR OFF CAMPUS – until authorized by the IACUC. AALAS is an association of professionals that advances responsible laboratory animal care and use to benefit people and animals. In my experience, the primary problem for IACUC proposals is that the criteria for removal from a study are often subjective. <> You will need to then complete the corresponding Animal Procedure “D” section(s) as separate file(s). Control and naive tissue, cells, and serum, Cytokine production by innate immune cells, EAE (experimental autoimmune encephalomyelitis), KLH or NP-KLH induced antibody production, TDAR (T cell dependent antibody response assay), Protocols for use with Hooke Kit™ Products, For information on contract research models, please see our CRO page, Cytokine Production Induced by T Cell Recall Response In Vitro, EAE Induction by Active Immunization in C57BL/6 Mice, EAE Induction by Active Immunization in Lewis Rats, EAE Induction by Active Immunization in SJL Mice, Immunization of Mice for Generation of Encephalitogenic T Cells, Immunization of Mice for Production of Antigen-Specific Antibodies, Methylated bovine serum albumin (mBSA) in PBS, Evaluation of compound effects on EAE development in C57BL/6 mice, Updated EAE protocol for active immunization in SJL mice, New EAE kit, PLP native peptide, serum from C57BL/6 and BALB/c mice. var info = 'info'; The Indianapolis IACUC protocol form is designed to include the required Core protocol application with a Protocol Associate (PA) Supplement form. If an IACUC Proposal is needed, click . var hookelaboratories = 'hookelabs.com'; var acode= '617 '; var ccode = '+1 '; An IACUC protocol must be submitted to describe the procedures to be done to animals in a research study here at UC Davis. Projects involving animal subjects may not begin until approved by the Committee, regardless of the type of the project or its source of funding. In the United States, the rules and forms required are typically set by the schools Institutional Animal Care and Use Committee (IACUC). endobj Research - Lab Animal Protocol Example IACUC Number PI PI Type General Faculty Department Research, Grants & Contracts PI Institution Co-PI's Research Staff External PIs Review Type Review Type Not Specified Approval Status Submitted By Anita Southwick Date Received Date of Completion Date Approved Three Year Expiration Date Proposed Start Date 07/31/2019 Date Closed Project … Guidance on Avoiding Excessive Amendments to IACUC Protocols . The IACUC is mandated to encourage the substitution of species more acceptable to society. [CDATA[ */ That includes both terrestrial and aquatic species, which were given greater emphasis in the … Most institutions have instituted an animal care and use protocol form that investigators are required to complete and submit to the IACUC. The IACUC Module also serves as a database of all protocols developed by the department and is a central source to view the most current version of a protocol in progress. Contact us for information about free samples If an IACUC Proposal is not needed, you may call Angela Bryant at 852-7307 to let the IACUC know that an iRIS Proposal Complete the General Questionnaire to determine necessary questions for your protocol and click Next. var open_href_start = ''; There is great variation in the length, format, content, and use of these forms, and a form that serves one institution well may not necessarily prove successful at another institution. Which of the following is an example of refinement per the three Rs of Russell and Burch? New protocols and Third Year Rewrites are generally reviewed by Full Committee Review (FCR). Examples: 1) Regional canine heartworm study. 46. Home; How to Search; Where to Search; Examples; How to Document; Classes; Get Help; PubMed searches with MeSH and textwords To refine the procedure by reducing pain. Although other individuals can help write or edit a protocol, the Principal Investigator (PI) must have a career staff position.). IACUC Protocol Task Force Document 1 . 6. IACUC Protocol Review_User Guide 9 Using Filters To Assist In The Review Process Filters enable quick navigation of the protocol. The IACUC will review the Animal Care and Use Protocol deviation and may send a letter to the Principal Investigator to communicate the importance of making sure that the actual work matches what is described in the Animal Care and Use Protocol. info + at + hookelaboratories + Sample IACUC protocol - Evaluation of compound effects on EAE development in C57BL/6 mice © 2008-2012 Hooke Laboratories, Inc. Your institutional IACUC committee may require changes or additions; these are only a starting point. Zebrafish (Danio rerio) are ideal for these studies. A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies . Examples not requiring power calculations include: pilot studies, tissue harvesting, breeding colony maintenance, etc. open_href_end + Note: The IACUC requires applications for protocol approval to be received two weeks before the expected beginning of the experiment. ]� |D�U;��c�������d��Ǩ��-�:��j���e%0Z����d�c���EUWe�vW��?�Ҩm��oUm� %���� LD50 experiments, long-term food or water deprivation, etc.). 5. These documents are sample IACUC protocols, offered as a convenience to our customers. WSU IACUC Policies #1: Adequate animal care in study area and satellite animal housing locations (8/2020). var mailto = 'mailto:'; Please see our FAQ, document.write(ccode + acode + exch + num); For example, if a National Institutes of Health (NIH) award is funding, in whole or in part, the activities on an IACUC animal use protocol, the PI of the IACUC animal use protocol is not required to be the same PI named on the NIH grant. 2 0 obj True. Forms can be submitted to researchcompliance@kent.edu. IACUC Protocol Application for Animal Use Instructions being (for example, more effective analgesia and anesthesia, less-invasive surgical techniques, terminating experiments at earlier stages of morbidity). 1. We sell direct in most countries. Provide a summary of the project in lay language in the Project Overview section (General Information Tab). 0.5, 1.5, 2.5, 3.5) when the clinical picture lies between two defined scores. info + at + hookelaboratories + /* ]]> */. to try in your own lab. ( ) C- Procedures will be invasive and may cause prolonged physiological or psychological stress. For example, criteria might include state- ments such as “animals will be euthanized if pain or distress is observed”. YOUR … /* '; Sample IACUC protocol forms. This protocol application is to be used for research, testing, teaching, and breeding activities with any vertebrate animals at Cal Poly Pomona. This guides helps you search the literature for alternatives to painful and distressful procedures in animal research. Sample IACUC Protocols. var at = '@'; overview of the IACUC protocol review and approval process, the criteria that the IACUC uses for evaluations, and the type of information that should be included in the various sections of the protocol form. <> B. Examples of protocol deviations include, but are not limited to: Failure to follow written IACUC protocol procedures, failure to obtain IACUC approval for a change in the research design, failure to report a known adverse event to the IACUC. If your lab wants to modify the procedure, that’s fine – but you’ll need to describe this in the protocol. These documents are sample IACUC protocols, offered as a … endobj IACUC/Animal Protocol. call us at or email The IACUC reserves the right to request additional information and may withhold approval from protocols that do not meet criteria for humane use of animals. stream ���d;����+tp�hR�,E#ݰ̇Z�p��X�oG'`d�Z��Ɖ���A���2�[Vh����b�c��ؚ�D�^�G����{R�HPU}�>�߰�5܃s6�����'�X!�o'�_ΰ@�͆����4�{5g����1fA�@+)�Qj�]H���r|�vl����5܊�c����@��\�M�.��yo|[h�^G���/NZr/����=9�9l����=��Û�3�,J���5ԀV�&y��CFZz���6��t�ʒc�wqd4�rZy��U7�M�b��OY�����ݙ��zg��Vŕ1;����%^P�(Z��/ĺ&�=�)x�w��R5%�M1P@Vd ��`3U��8�ΏM% �k���\'W���^en|����ңz�ԅ1)�w{Z��y"eS�uZ�x��x^�̀��1s�F�~봳Q䕭����gc^���wF��Eݥecgj��y���Xel�J��D��zsqG��(F�=M%jfDo��h2�*F��h��]�Y���+��]���Q����uDG!����Ka������V�e.�51#>�6��I��_K��t��,Xͨ^���ٍ�)#�u��8����� From the Manage Protocols screen, click +New Protocol and select IACUC; Complete the General Information questions and click Next. The various topics the IACUC evaluates on the protocol include the rationale for proposed … document.write(open_href_start + mailto + Please contact us with your ideas or proposals. These standard procedures are already IACUC approved, so all you have to do is check a box, and RIO will add the procedure to your protocol. tu��Me�r1Wa�*d���_~t�O��8���2ĩ�!��K��""��ѩ�f��[G��)�pK`U�{��p���g(P����?a�'�==����(��]ש7Bw�+�� �K~]����+�LQ��n�h�{#��)LU�����%�yp1R MBV��m�e6NL! 3 0 obj IACUC Protocol Narrative – Sections 1-9 3. k��֙ي8��8v/}�z�eXbo�i„���-�'�������� ���UE�^�b��3!ԅ}�NyE�#I��]n�L��.�[�{}�s*�n��"h{m�}���3r���b$��"�T[�Ά �h 1_��sI-m�4�+,�oG՜EE��и�^�"�T��B�~ܟ$�p�Շ���.�5 �'H���tN���G���*�xA���w��[�����s�d�w�cf^�8�Z�NB����Q���gH��'�{_;�g���9J˭U��C�J&0u*�܁��,�Τe��8Uɔ�I�*�R��&m�M��c(�������J�˹3�j�dHm���v�\[]s�݆���v��\����k2w�+n�L�O�K�j�o0nyk���c\t�5C��З�j�{W����Ũ"���d�[JE����2�AΎ���@흁�Dm|$m(�bħ��@j�2=��"�WPe����BU��9d�ij�9M�ob�A]Hps�uU^�B�R�j4��t�)҈�SxA��qյ�QJ�w(ZM��A�V�>Uk������ޭ �w��ѱj�O@Z �w5)��n�3���3oA=�Yŧ8��2��'���u�n�̚��t�s'Y_pW[�@���6�F'��a��r���C��&(��i|�+���͌��Ц,����M���&��o� Pain, considerable distress, or discomfort may be induced and not mitigated by anesthesia or adequate analgesia (e.g. permit the investigator to summit their protocol to the IACUC on-line. ��x����h��p��Yw]�8_ݾ����W1$j�����%�a\�Ymm���rz�+�!�@TuZ�F�~���!��ǥ;�Ԥۺ? You must justify the number of groups in repeated studies in addition to justifying the number of animals per group. The IACUC Protocol Search function in CoeusLite provides a User with the capability of quickly locating both historic protocols and protocols which are currently being developed. Page 3 of 5 Scoring is on the scale of 0 to 5, according to the table below. IACUC Protocol Version, January 2019. IACUC protocols must be renewed annually with a de novo review every 3 years. The Brown IACUC does not require that the PI of an IACUC protocol be the PI of any or all corresponding funding sources cited on the protocol. 4 0 obj This page offers protocols for use with our Hooke Kit™ products. Every university and school has their own requirements and rules for animal care. 1 0 obj x��=io�ƒ� �?�_4�Ͱ�I6�,H����l'�-��rdI��$�_�u�IrDE������GwWuu�}p���[_?P]-^��}K-J���m��YX��]���ޜ�sW�o�z��|�l�,���e�������/^�p��}hzW�Wm�5 ��B���n�0_�y��X����蚢��&��;�Ԡ 6��@;г���� An IACUC protocol must be approved BEFORE … Coeus Lite is the web-based version of the Coeus application. [CDATA[ */ endobj We invite collaboration with academic laboratories in areas of mutual interest. IACUC Forms Office of Research Compliance | Please complete and submit the appropriate form. For example, it may be helpful to view comments submitted by others prior to a meeting. Protocols will be reviewed by the IACUC at the next scheduled meeting. Mice may be given “in-between” scores (i.e. Credit to Hooke Laboratories is requested as a courtesy, but is not required. Questions about Material Transfer Agreements can be directed to Technology Commercialization. Contact us to place your order or for a quote. <> var exch = '475 '; Some specific examples are also provided. In the Procedures Check List section (A02) of the Core protocol, please check the specific animal procedures which apply to your protocol. A protocol deviation is any departure from methods approved in an IACUC protocol. /* */ Progress Report: Required ONLY if the application is a three-year de-novo review of an ongoing, project previously approved by the IACUC. <>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S>> 4. Helpful hints when using standard procedures: Make sure you read the procedure carefully before checking the box! !-�#U������|�� ���*]���͆:��Y�آ�-UQ�^b����Z��CT ]��e��SxD%w���-�莞cS�:)���|"�}��F�*��z��1�z��ISՅ����A�A[�fѴЀ�gC5U�&��Lj�/U �0�O�p{|?�����R��� OAɔ��lZ���$��_"m���a��L��ٗ�Al�0uZ�s�܇n��h1��N�5 )�ƖE���{��R�@��^],[�O7o�'�:\ꒋ���9�~�ϰ�)>� 45. 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